01 - Heat a large skillet over medium-high heat. Add ground beef, salt, pepper, smoked paprika, and garlic powder. Break up meat and stir occasionally until browned and cooked through, approximately 7–8 minutes. Drain excess fat if needed.
02 - In a small bowl, whisk together mayonnaise, ketchup, mustard, pickle relish, apple cider vinegar, smoked paprika, salt, and pepper until smooth and well combined. Set aside.
03 - Evenly distribute chopped romaine lettuce among four large serving bowls to create the base layer.
04 - Top each bowl with equal portions of cooked ground beef, cherry tomatoes, cheddar cheese, red onion slices, pickle slices, and diced avocado.
05 - Drizzle each bowl with prepared burger sauce just before serving. Serve immediately while components are fresh.